Full Schedule

8:15 AM - 9:15 AM MST

Epigenetic Clocks, Aging, and Cancer

Location: Grand Ballroom, Lower Concourse

Co-Moderator: – Medical College of Wisconsin

Co-Moderator: – Children's Hospital Los Angeles, University of Southern California

CE: 1.0

8:15 AM - 9:15 AM MST

DNA Hypomethylation Restrains Malignant Progression

Location: Grand Ballroom, Lower Concourse

Speaker: – Dana-Farber Cancer Institute

OncologyInherited Conditions

CE: 1.0

10:15 AM - 11:45 AM MST

Exploring the Utility of Multiplex Infectious Disease Panel Testing for Diagnosis of Infection in Different Body Sites: A Joint Report of the AMP, American Society for Microbiology, Infectious Diseases Society of America, and Pan American Society for Clinical Virology

Location: 255BC, Second Level

Moderator: – NY State Dept of Health Wadsworth Center

Infectious Diseases

CE: 1.50

10:15 AM - 10:45 AM MST

Exploring the Utility of Multiplex Infectious Disease Panel Testing for Diagnosis of Infection in Different Body Sites: A Joint Report of the AMP, American Society for Microbiology, Infectious Diseases Society of America, and Pan American Society for Clinical Virology

Location: 255BC, Second Level

Speaker: – MEMORIAL SLOAN KETTERING CANCER CENTER

Infectious Diseases

CE: 1.50

10:45 AM - 11:45 AM MST

Panel Discussion

Location: 255BC, Second Level

Panelist: – MEMORIAL SLOAN KETTERING CANCER CENTER

Panelist: – Children's Hospital Los Angeles; University of Southern California

Panelist: – University of Washington

Infectious Diseases

CE: 1.50

10:15 AM - 11:45 AM MST

Machine Learning Applications in Healthcare and Considerations for Building Effective Models

Location: 251, Upper Concourse

Co-Moderator: – Memorial Sloan Kettering Cancer Center

Co-Moderator (Early Career): – University of Utah, ARUP labs

CE: 1.50

10:15 AM - 10:45 AM MST

AI/ML Pipeline to Identify Genetic Biomarkers and Predict Disease for Precision Medicine

Location: 251, Upper Concourse

Speaker: – Rutgers Institute for Health, Health Care Policy and Aging Research. Rutgers Robert Wood Johnson Medical School. Rutgers Biomedical and Health Sciences. Rutgers, The State University of New Jersey.

AdvocacyInformatics

CE: 1.50

10:45 AM - 11:15 AM MST

"Weakly-Supervised Tumor Purity Prediction from Frozen H&E Stained Slides"

Location: 251, Upper Concourse

Speaker: – WEII CORNELL MEDICINE

AdvocacyInformatics

CE: 1.50

11:15 AM - 11:45 AM MST

Approaches and Techniques to Consider when Building Machine Learning Models

Location: 251, Upper Concourse

Speaker:

AdvocacyInformatics

CE: 1.50

10:15 AM - 11:45 AM MST

Rapid Molecular Diagnostics

Location: 250, Upper Concourse

Co-Moderator: – University of California

Co-Moderator: – Children's Hospital Los Angeles, University of Southern California

Co-Moderator: – Columbia University

10:15 AM - 10:45 AM MST

Rapid Ion Semi-Conductor Based Nucleic Acid Sequencing as an Enabler of Personalized Oncology

Location: 250, Upper Concourse

Speaker: – Memorial Sloan Kettering Cancer Center

10:45 AM - 11:15 AM MST

Rapid Whole Genome Sequencing in Newborns & Children with Undiagnosed Diseases

Location: 250, Upper Concourse

Speaker: – Rady Children’s Institute for Genomic Medicine

CE: 1.50

11:15 AM - 11:45 AM MST

Rapid Molecular Diagnostics

Location: 250, Upper Concourse

Speaker: – Memorial Sloan Kettering Cancer Center

10:15 AM - 11:45 AM MST

Technologist Innovation Session

Location: 355BC, Third Level

CE: NOT CME/CMLE

10:15 AM - 10:20 AM MST

Opening Remarks

Location: 355BC, Third Level

CE: NOT CME/CMLE

10:20 AM - 10:40 AM MST

TT048 - Reducing Thermocycler Ramp Rate Improves Coverage of GC-rich Regions in the Illumina TruSight Oncology 500 Assay

Location: 355BC, Third Level

Speaker: – Weill Cornell Medicine

CE: NOT CME/CMLE

10:40 AM - 11:00 AM MST

TT049 - Multiple Consecutive Quality Checkpoints Significantly Improve the Value of Biobanked Samples for Research

Location: 355BC, Third Level

Speaker: – Reference Medicine

CE: NOT CME/CMLE

11:00 AM - 11:20 AM MST

H043 - Redesigning C-Terminal Primers for Accurate Sequencing of ABL1 Domain in BCR::ABL1 Positive Patients

Location: 355BC, Third Level

Speaker: – Center for Advanced Molecular Diagnostics, Brigham & Women’s Hospital

CE: NOT CME/CMLE

11:20 AM - 11:40 AM MST

G074 - Using Genotyping-based Mendelian Error Analysis to Identify and Minimize the Risk of Sample Misidentification in Trio Exome Sequencing Service

Location: 355BC, Third Level

Speaker: – Stanford Health Care

CE: NOT CME/CMLE

11:40 AM - 11:45 AM MST

Closing Remarks

Location: 355BC, Third Level

CE: NOT CME/CMLE

10:15 AM - 11:45 AM MST

What's in a Name? HGVS and Nomenclature for Genomics - Past & Future

Location: 255EF, Second Level

Co-Moderator: – University of Texas MD Anderson Cancer Center

Co-Moderator (Early Career): – Washington University School of Medicine

CE: NOT CME/CMLE

10:15 AM - 10:45 AM MST

Aligning HGVS Nomenclature System with Laboratory and Healthcare Provider Needs - The CAP Perspective

Location: 255EF, Second Level

Speaker: – Birgit Funke Consulting LLC

Informatics

CE: NOT CME/CMLE

10:45 AM - 11:15 AM MST

HGVS Nomenclature in 2023: Recent Updates, Modernization, and Community Engagement

Location: 255EF, Second Level

Speaker: – MyOme, Inc.

Informatics

CE: NOT CME/CMLE

11:15 AM - 11:45 AM MST

What's in a Name? HGVS and Nomenclature for Genomics - Past & Future (Q & A)

Location: 255EF, Second Level

Speaker: – MyOme, Inc.

Speaker: – Birgit Funke Consulting LLC

Informatics

CE: NOT CME/CMLE

1:15 PM - 1:45 PM MST

AMP Working Group: Provider-Friendly Molecular Biomarker Reports

Location: 251, Upper Concourse

Speaker: – Univ of Central Florida College of Medicine

OncologyLab Management

1:15 PM - 2:15 PM MST

AMP Working Group: Provider-Friendly Molecular Biomarker Reports

Location: 251, Upper Concourse

Moderator: – Columbia University Medical Center

1:45 PM - 2:15 PM MST

Panel Discussion for Working Group: Provider-Friendly Molecular Biomarker Reports

Location: 251, Upper Concourse

Panelist: – Univ of Central Florida College of Medicine

Panelist: – University of Michgian

Panelist: – University of Utah

Panelist: – University of Arkansas for Medical Sciences

Panelist: – OHSU

OncologyLab Management

1:15 PM - 2:15 PM MST

AMP Working Group: Standardization of Pharmacogenomics Alleles

Location: 250, Upper Concourse

Moderator: – Mayo Clinic

CE: NOT CME/CMLE

1:15 PM - 1:45 PM MST

AMP Working Group: Standardization of Pharmacogenomics Alleles

Location: 250, Upper Concourse

Speaker: – University of North Carolina at Chapel Hill

Lab ManagementInherited ConditionsMolecular Methodologies & Technologies

CE: NOT CME/CMLE

1:45 PM - 2:15 PM MST

Panel Discussion: AMP Working Group: Standardization of Pharmacogenomics Alleles

Location: 250, Upper Concourse

Panelist: – University of North Carolina at Chapel Hill

Panelist: – Centers for Disease Control and Prevention

Panelist: – Stanford University

Panelist: – AccessDx Laboratory

Lab ManagementInherited ConditionsMolecular Methodologies & Technologies

CE: NOT CME/CMLE

1:15 PM - 2:15 PM MST

Platform Presentations of Selected Informatics Abstracts

Location: 255BC, Second Level

Co-Moderator: – Geisinger

Co-Moderator (Early Career): – Childrens Hospital Los Angeles

Platform Presentation

CE: 1.0

1:15 PM - 1:30 PM MST

I018 - Tumor Mutational Burden (TMB) Scoring in Pediatric Tumors Using a Comprehensive Clinical Genomics Sequencing Approach

Location: 255BC, Second Level

Poster Presenter: – St Jude Children's Research Hospital

Platform Presentatation

CE: 1.0

1:30 PM - 1:45 PM MST

I034 - Normalization of Real-World Sequence Variant Data from Heterogeneous Sources

Location: 255BC, Second Level

Poster Presenter: – Syapse

Platform Presentation

CE: 1.0

1:45 PM - 2:00 PM MST

I019 - Deep Learning Applications Using H&E Images Improve Clinical Sequencing Workflows

Location: 255BC, Second Level

Poster Presenter: – Providence Health and Services

Platform Presentation

CE: 1.0

2:00 PM - 2:15 PM MST

I002 - Large-Scale Mining of More Than 65,000 Karyotypes in the Mitelman Database Identifies Unexpected Differences and Similarities Between Lymphoid, Myeloid, and Solid Tumors

Location: 255BC, Second Level

Poster Presenter: – The Ohio State University

Platform Presentation

CE: 1.0

1:15 PM - 2:15 PM MST

Platform Presentations of Selected Solid Tumors Abstracts

Location: 255EF, Second Level

Co-Moderator (Early Career): – Columbia University Irving Medical Center

Co-Moderator: – Foundation Medicine Inc

Platform Presentation

CE: 1.0

1:15 PM - 1:30 PM MST

ST005 - More Accurate Measures of Disease Burden: A Strategy for Absolute Quantification of Plasma Biomarker Levels Reduces Interference From Wild Type DNA

Location: 255EF, Second Level

Poster Presenter: – University of North Carolina School of Medicine

Platform Presentation

CE: 1.0

1:30 PM - 1:45 PM MST

ST012 - S DNA Damage Response Gene Expression Profile Distinguishes Poor-Acting IDH-Mutant Gliomas With Shared Methylome Signatures

Location: 255EF, Second Level

Poster Presenter: – University of North Carolina School of Medicine

Platform Presentation

CE: 1.0

1:45 PM - 2:00 PM MST

ST121 - High Degree of NGS Concordance in a 9-Laboratory Study: Data From the Genomics Organization for Academic Laboratories

Location: 255EF, Second Level

Poster Presenter: – U of Chicago

Platform Presentation

CE: 1.0

2:00 PM - 2:15 PM MST

ST030 - Mutational Signature Analysis by SigMa Across Major Cancer Subtypes Reveals Previously Undescribed Associations

Location: 255EF, Second Level

Poster Presenter: – Memorial Sloan Kettering Cancer Center

Platform Presentation

CE: 1.0

1:15 PM - 2:15 PM MST

Platform Presentations of Selected Tech Topics Abstracts

Location: 355BC, Third Level

Co-Moderator: – Duke University Health Systems

Co-Moderator (Early Career): – Icahn School of Medicine at Mount Sinai

Platform Presentation

CE: 1.0

1:15 PM - 1:30 PM MST

TT053 - Tissue Prior the Initial H&E Section As Alternative Source of DNA for Molecular Diagnostics

Location: 355BC, Third Level

Poster Presenter: – University Health Network

Platform Presentation

CE: 1.0

1:30 PM - 1:45 PM MST

TT008 - Assessment of Stability and Alternative Specimen Sources for the Clinical Validation of a Sample-To-Answer BCR::ABL p190 Assay in a Low-Prevalence Setting

Location: 355BC, Third Level

Poster Presenter: – Washington University School of Medicine

Platform Presentation

CE: 1.0

1:45 PM - 2:00 PM MST

TT058 - Evaluation of Hi-C Sequencing as a Novel Diagnostic Technology for Detecting Genomic and Chromosomal Structural Variants in Constitutional Disorders

Location: 355BC, Third Level

Poster Presenter: – University of Washington

Platform Presentation

CE: 1.0

2:00 PM - 2:15 PM MST

TT013 - Variant Calling Behind Threshold Lines: Lowering Levels of Detection Through Precise Error Modeling

Location: 355BC, Third Level

Poster Presenter: – Children's Hospital Colorado

Platform Presentation

CE: 1.0

2:30 PM - 4:00 PM MST

Cloud Versus Local Compute

Location: 255BC, Second Level

Co-Moderator: – Geisinger

Co-Moderator (Early Career): – Memorial Sloan Kettering Cancer Center

CE: 1.50

2:30 PM - 3:15 PM MST

The Cloud Conundrum

Location: 255BC, Second Level

Speaker: – Dartmouth

Informatics

CE: 1.50

3:15 PM - 4:00 PM MST

Regulatory and Cybersecurity Considerations for Serving NGS Applications Locally Versus from the Cloud

Location: 255BC, Second Level

Speaker: – Children's Healthcare of Atlanta

Informatics

CE: 1.50

2:30 PM - 4:00 PM MST

From Crowdsourcing to Somatic ClinGen Variant Curation Expert Panels (SC-VCEPs): Navigating Variant Curation in Somatic Cancer Genomics

Location: 255EF, Second Level

Co-Moderator: – University of Texas MD Anderson Cancer Center

Co-Moderator (Early Career): – Cedars Sinai

CE: 1.50

2:30 PM - 2:55 PM MST

An Introduction to the ClinGen Somatic Cancer Organization and Procedures

Location: 255EF, Second Level

Speaker: – Washington University School of Medicine

CE: 1.50

2:55 PM - 3:20 PM MST

CIViC: An Open Community Platform For Variant Curation

Location: 255EF, Second Level

Speaker: – Washington University School of Medicine

CE: 1.50

3:20 PM - 3:45 PM MST

Somatic Cancer Variant Curation Expert Panels (SC-VCEPs) and Their Pursuit of Oncogenicity Interpretations for SNVs and Fusions

Location: 255EF, Second Level

Speaker: – Washington University School of Medicine

CE: 1.50

2:30 PM - 4:00 PM MST

Molecular Characterization and Classification of Aggressive B-Cell Lymphomas

Location: 355BC, Third Level

Co-Moderator: – Columbia University

Co-Moderator (Early Career): – University of Pennsylvania

CE: 1.50

2:30 PM - 3:15 PM MST

Molecular Characterization and Classification of Aggressive B-Cell Lymphomas

Location: 355BC, Third Level

Speaker: – Dana-Farber Cancer Institute

OncologyMolecular Methodologies & Technologies

CE: 1.50

3:15 PM - 4:00 PM MST

A Practical Approach to Molecular Testing in Aggressive B-Cell Lymphoma

Location: 355BC, Third Level

Speaker: – Johns Hopkins University School of Medicine

OncologyMolecular Methodologies & Technologies

CE: 1.50

2:30 PM - 4:00 PM MST

Tackling the MolDx Technical Assessment: Techniques for Successfully Completing the Assessment and Integrating the Assessment Process into Your Laboratory Validation Procedure

Location: 250, Upper Concourse

Co-Moderator: – Duke University Health Systems

Co-Moderator (Early Career): – Department of Pathology, Augusta University

CE: 1.50

2:30 PM - 3:15 PM MST

Tackling the MolDx Technical Assessment: Techniques for Successfully Completing the Assessment and Integrating the Assessment Process into Your Laboratory Validation Procedure.

Location: 250, Upper Concourse

Speaker: – Palmetto GBA

Molecular Methodologies & Technologies

CE: 1.50

3:15 PM - 4:00 PM MST

Tackling the MolDx Technical Assessment: Techniques for Successfully Completing the Assessment and Integrating the Assessment Process into Your Laboratory Validation Procedure.

Location: 250, Upper Concourse

Speaker: – Duke University Health System

Molecular Methodologies & Technologies

CE: 1.50

2:30 PM - 4:00 PM MST

The Use of Genomic Biomarkers for Check-Point Inhibitor Response Assessment: A Discussion of Two Trials and Biomarkers

Location: 251, Upper Concourse

Co-Moderator: – Foundation Medicine Inc

Co-Moderator (Early Career): – University of Kentucky

CE: 1.50

2:30 PM - 3:15 PM MST

ImmunoMATCH Biomarker Selection and Possible Advantages of Multi-Analyte Assays

Location: 251, Upper Concourse

Speaker: – Frederick National Laboratory for Cancer Research- Leidos Biomedical Research Inc

CE: 1.50

3:15 PM - 4:00 PM MST

A Review of NCI-MATCH ARM Z1D: Treatment of MMR Deficient Solid Tumors with Nivolumab

Location: 251, Upper Concourse

Speaker: – NIH/NCI

CE: 1.50

4:15 PM - 5:15 PM MST

Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer

Location: 250, Upper Concourse

Co-Moderator: – Memorial Sloan Kettering Cancer Center

Co-Moderator: – Duke University Health Systems

CE: 1.0

4:15 PM - 4:45 PM MST

Guidelines and Standards for Classification, Interpretation and Reporting of Somatic Sequence Variants in Cancer

Location: 250, Upper Concourse

Speaker: – National Center For Tumor Diseases

OncologyMolecular Methodologies & Technologies

CE: 1.0

4:45 PM - 5:15 PM MST

Standardized Nomenclature in Reporting Sequence Variants in Cancer

Location: 250, Upper Concourse

Speaker: – Nationwide Children's Hospital

OncologyMolecular Methodologies & Technologies

CE: 1.0

5:15 PM - 5:30 PM MST

Closing Remarks

Location: 250, Upper Concourse