Revolutionizing Cytogenomics with Optical Genome Mapping in Hematological Malignancies
Wednesday, November 15, 2023
1:00 PM – 1:50 PM MST
Optical Genome Mapping (OGM) is emerging as a leading new method to assess the cytogenomic profile of hematological malignancies, as shown by the mounting evidence presented in peer-reviewed publications worldwide. Not only has OGM been shown to be highly concordant with classical methods in the detection of structural and numerical variants, but it has also been demonstrated to reveal multiple incremental pathogenic variants. Additionally, it is transforming lab workflows by enabling consolidation of multiple assays into a single assay.
This session will start with a brief introduction on OGM by Dr. Hastie, followed by Dr. Dubuc and Dr. Crocker presenting clinical research data generated using OGM across different types of hematological malignancies, including lymphomas, myelomas and leukemias. The session will end with Dr. Smith discussing an international working group initiative and proposed framework for standardized implementation of OGM across cytogenetic labs.