Professor, Department of Laboratory Medicine and Medicine / Infectious Diseases UCSF San Francisco, California, United States
Session Description: This is part 1 of two breakout sessions that will focus on genome sequencing approaches and applications in clinical microbiology and public health laboratories. In this session, we will focus on: 1) targeted sequencing and its utility for diagnosis, genotyping, and antiviral resistance, 2) pathogen agnostic metagenomic sequencing and its utility for challenging diagnoses. The session will educate different level attendees on wet lab methodologies, approaches and challenges of data analyses, laboratory implementation, and clinical applications. The clinical utility of deep sequencing versus traditional Sanger based methods will be discussed. The utility of host transcriptomic data for diagnosis will also be discussed.
Learning Objectives:
To provide an overview of methodology of targeted sequencing in medical microbiology (bacteriology, virology, mycobacteriology, and mycology)
To detail options for bioinformatics databases and analyses
To understand the clinical utility and applications of targeted and agnostic sequencing