Professor, Department of Pathology and Laboratory Medicine The University of British Columbia Vancouver, British Columbia, Canada
Session Description: This joint solid tumor and hematopathology session will explore recent advances in single cell genomics and spatial biology. Speakers will describe new tools that facilitate granular characterization of the tumor microenvironment and its impact on cancer biology. Topics in the session will span solid tumor and hematological malignancies. Cancer patient responses to therapy are driven not just by the cellular content of tumors, but also their spatial organization. Recent progress with single cell transcriptomics and histology imaging techniques has enabled comprehensive spatial characterization of tumor microenvironment in solid tumors and Hodgkin Lymphoma biology providing new avenues for molecular classification and biomarker development. Tools in development for dissecting and analyzing these relationships, particularly in the context of immunotherapy will be discussed.
Learning Objectives:
Upon completion, participants will be able to describe spatial genomic tools utilized to advance our understanding of cancer cell biology
Upon completion, participants will be able describe the important role of tumor microenvironment in solid tumors and hematological malignancies
Participants will learn about new insights into Hodgkin lymphoma pathogenesis by spatially resolved single cell studies