Director of the Molecular Characterization Laboratory @FNLCR
NIH/NCI
Frederick, Maryland, United States
Mickey directs the Molecular Characterization Laboratory (MoCha) which was established to develop state-of-the-art molecular assays to support clinical research and clinical trials. Projects include development and implementation of analytically validated NGS assays for patient screening in NCI-sponsored trials (e.g. NCI-MATCH, Pediatric MATCH, MyeloMATCH, and iMATCH) as well as a pan cancer circulating tumor DNA assay. MoCha provides genomic characterization for the NCI’s Patient Derived Model Repository and participates in development of multiple reference materials and clinical assay harmonization projects.
His career started at Genentech, where he developed novel assays to support clinical studies and discover new therapeutic targets. He was the author of the first quantitative “real-time” PCR papers and contributed to the development of this powerful technology. Prior to FNLCR while at Roche Molecular Diagnostics, he managed two large multi-national clinical assay studies: The MILE Study (microarray innovations in leukemia), and a collaboration with the Leukemia and Lymphoma Molecular Profiling Project. He also initiated 2 projects that subsequently were approved by the FDA as IVD tests. He has published over 70 manuscripts and is an inventor on over 30 issued U.S. Patents. Mickey received his Ph.D. from the University of Virginia.
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A Review of NCI-MATCH ARM Z1D: Treatment of MMR Deficient Solid Tumors with Nivolumab
Saturday, November 18, 2023
3:15 PM - 4:00 PM MST