Reagents for Molecular Diagnostics Workflows: Removing Barriers for Assay Developers

Nucleic acid enzymes have long powered the chemistries of molecular diagnostics, and as the field moves to rapid POC and field settings, new demands are placed on DNA polymerases, reverse transcriptases, and other key enzymes. Through protein engineering, discovery, and novel mechanisms for control of enzymatic activities, New England Biolabs is enabling this new generation of diagnostic applications. Methods and reagents for isothermal amplification and RT-qPCR in particular can benefit from enzyme innovation, robust development, and lyophilization and we will present how our approaches to building better tools and services has benefited both core and developing applications of molecular diagnostics.