OncoSIGNal Platform for Analysis of Cell Signaling Pathway Activity Unlocking the Power of Personalized Targeted Therapies
Wednesday, November 15, 2023
3:00 PM – 3:50 PM MST
NGS often does not identify actionable mutations. We present the OncoSIGNal platform that enables functional tumor profiling measuring the activity of critical cell signaling pathways. Results are actionable across tumors, creating new opportunities for personalized targeted treatment. The activity of 7 pathways (ER, AR, PI3K, MAPK, TGFb, HH, Notch) are measured in FFPE tissue using the OncoSIGNal RT-qPCR test or RNA-seq full transcriptome data as input. In this workshop Dr. M. Snuderl (Head Pathology, NYU-Langone) will discuss application of OncoSIGNal in breast cancer and Dr. F.C. de Jong (Erasmus Medical Center, NL) for response prediction to BCG in bladder cancer.