Associate Professor Johns Hopkins University School of Medicine Baltimore, Maryland, United States
Session Description: Aggressive B-cell lymphomas comprise a heterogeneous group of biologically distinct tumors with overlapping morphologic, immunophenotypic, and clinical characteristics. Sophisticated multi-omic studies have expanded our understanding of the underlying genetic basis of these lymphomas, leading to several recently proposed genetics-based subgroups. Because implementation of these advanced research technologies and bioinformatics may not be currently feasible for all clinical laboratories, there is a need for simplified strategies to generate and interpret clinically relevant mutational data. This session will explore the recently proposed genetics-based subgroups and present a practical framework for routine molecular testing in clinical laboratories.
Learning Objectives:
Upon completion, participants will be able to describe the laboratory and bioinformatic techniques used to generate genetic subtypes of DLBCL.
Upon completion, participants will be able to compare and contrast the genetic DLBCL subtypes as proposed by different research groups.
Upon completion, participants will be able to formulate a practical laboratory strategy to generate and interpret genetic data for aggressive B-cell lymphomas.
.jpg "Rena R. Xian, MD (she/her/hers) photo")